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ea0022p585 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

The metabolic syndrome (MetS) in 2610 GH deficient (GHD) subjects before GH replacement: a KIMS (Pfizer International Metabolic Database) analysis

Verhelst Johan , Mattsson Anders F , Luger Anton , Thunander Maria , Goth Miklos , Koltowska-Haggstrom Maria , Abs Roger

Objective: To identify MetS and non-MetS in subjects with adult-onset GHD before start of GH replacement and to compare prevalence of cardiovascular risk factors.Subjects and methods: MetS was defined (IDF criteria) by the obligatory presence of increased waist circumference (WC) and presence of at least two of following components: hypertension, decreased HDL-cholesterol, increased triglycerides, diabetes mellitus. The complementary group was defined as...

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ea0020p546 | Neuroendocrinology, Pituitary and Behaviour | ECE2009

The prevalence of diabetes mellitus in 9776 adult patients with childhood- and adult-onset growth hormone (GH) deficiency before GH replacement: a KIMS analysis

Abs Roger , Luger Anton , Wilton Patrick , Thunander Maria , Verhelst Johan , Goth Miklos , Koltowska-Haggstrom Maria , Mattsson Anders

Background: Untreated GH-deficiency (GHD) in adults has been suggested to be associated with an increased prevalence of type 2 diabetes mellitus (DM). Proposed causative factors are the tendency to overweight and the insulin resistance due to central adiposity.Patients and methods: The KIMS (Pfizer International Metabolic Database) was used to evaluate the prevalence of DM in both childhood-onset (CO; n=1977; 56% males) and in adult-onset (AO; ...

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Endocrine Abstracts

The metabolic syndrome (MetS) in 2610 GH deficient (GHD) subjects before GH replacement: a KIMS (Pfizer International Metabolic Database) analysis

The prevalence of diabetes mellitus in 9776 adult patients with childhood- and adult-onset growth hormone (GH) deficiency before GH replacement: a KIMS analysis

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